Narrative: Stiff Person Syndrome (SPS) is a neuro-immunological condition most frequently associated with the GAD65 autoantibody. Common treatments are benzodiazepines and intravenous immunoglobulin (IVIG).
The case presented is of a 66-year-old female diagnosed with SPS by a neurologist after more than a decade of worsening muscle spasms and subsequently confirmed with elevated levels of GAD65. Her condition was continuing to deteriorate despite IVIG, baclofen, botulinum toxin, and Chiropractic spinal manipulation.
The introduction of Meningeal Releases as taught as part of the chiropractic technique, Advanced BioStructural Correction™ combined with Chiropractic spinal manipulation was concomitant with progressive improvement in the condition of the patient, to the extent that the patient progressed from wheelchair bound to ambulatory within 9 months of beginning treatment. Further research to explore the causal relationship between meningeal tension and SPS may inform additional treatment options.
Indexing Terms: Chiropractic - Subluxation - ABC™ - Meningeal release - Stiff Person Syndrome
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