• de Carvalho J
• Lerner A
• Feingold D

• Adult
• Affiliation / Ariel University. Department of Behavioral Sciences
• Affiliation / Chaim Sheba Medical Center. Zabludowicz Center for Autoimmune Diseases
• Affiliation / Federal University of Bahia Salvador. Rheumatology
• Affiliation(G) / Brazil / Bahia
• Affiliation(G) / Israel / Ariel
• Affiliation(G) / Israel / Tel HaShomer
• Cannabis
• Dietary Supplements
• Hydrocortisone / deficiency
• Hyperhomocysteinemia
• Male
• Marijuana Abuse
• Open Access Document
• Vitamins / therapeutic use

Objective: The purpose of this study was to describe the management of 2 long-term users of cannabis with nutrition and psychotherapy.

Clinical Features: A 28-year-old man presented with a medical history of asthma, depression, anxiety, and smoking, and was a long-term user of cannabis for 9 years (usually 3 times a week). A 39-year-old man presented with a medical history of anxiety and fatigue, and was a long-term user of cannabis for 14 years (usually twice a week). Laboratory tests showed altered blood levels of homocysteine, vitamins, and cortisol.

Intervention and Outcome: Both patients were given supplements of vitamins (folic acid, methylcobalamin, and pyridoxine), vitamin D, Rhodiola rosea, and L-tyrosine. Psychotherapy also was provided to both patients. After 2 months of treatment, both patients improved and reduced their cannabis consumption.

Conclusion: This study describes vitamin deficiencies, low cortisol levels, and hyperhomocysteinemia in 2 cannabis users who were managed with a combination of nutritional supplements and psychotherapy.

Author Keywords:  Hyperhomocysteinemia; Cannabis; Marijuana Abuse; Vitamins; Dietary Supplements

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