• Zodkoy S

• Biofilms
• Biological Products
• Child
• Enzymes
• Fibrinolytic Agents
• Male
• Mevalonate Kinase Deficiency

Abstract: Periodic Fever Syndrome (PFS) is highlighted by a fever with or without additional symptoms. The underlying cause
is suspected to be hereditary in nature from a genetic mutation. An underlying cause that is not commonly considered
or diagnosed is a biofilm-related infection. A biofilm’s natural cycle of growth-release-repeat provides an episodic
flow of microorganism into the body to cause a fever and the asymptomatic periods in-between typical in a PFS
patient. The microorganisms being released can be bacterial, viral, fungal or a combination which triggers the periodic
fevers while the biofilm acts as a barrier hiding the infection from detection and drug therapies. A treatment protocol
using fibrinolytic enzymes and a broad-spectrum antimicrobial may be an effective treatment for PFS not associated
with a genetic mutation.

Author keywords: Periodic Fever Syndrom, Biofilms, Fibrinolytic enzymes, Nattokinase, Serrapeptase

This abstract is reproduced with the permission of the publisher.