Index to Chiropractic Literature
Index to Chiropractic Literature
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Monday, October 27, 2025
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Article ID
Title
URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Citation&list_uids=15800509
Journal J Manipulative Physiol Ther. 2005 Feb;28(2):122-127
Author(s)
Subject(s)
Peer Review Yes
Publication Type Article
Abstract/Notes BACKGROUND: Cervical spine manipulation is one of the many interventions practiced by health professionals to treat musculoskeletal disorders of the cervical spine. Although serious consequences of manipulation have been documented, the incidence is thought to be rare. More frequently, there may be minor transient side effects after manipulation of the cervical spine, such as headache, dizziness, and nausea. One of the hypothesis is that these side effects are caused by ischemia in the areas perfused by the vertebral arteries.

OBJECTIVE: The purpose of this study was to investigate whether manipulation of the cervical spine can influence blood flow in the brain.

METHODS: Single photon emission computed tomography was used to examine changes in regional cerebral blood flow caused by cervical spine manipulation (CSM) performed by a physiotherapist to 15 volunteers, using a 1-day split-dose Technetium 99m-ethyl cysteinate dimer single photon emission computed tomography activation paradigm.

RESULTS: One brain region was identified showing a decreased regional cerebral blood flow after manipulation. This region was situated in the anterior lobe of the left cerebellum (-42, -48, -24).

CONCLUSIONS: These findings suggest that cerebellar hypoperfusion may occur after CSM. This could explain why certain people experience headache, dizziness, or nausea after CSM. Further investigation into patient symptoms in the presence of cerebellar hypoperfusion and the possible link of these findings with other adverse reactions are warranted.

Click on the above link for the PubMed record for this article; full text by subscription. The abstract is reproduced here with the permission of the publisher.

      

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